Without question, the most infamous individual Vampire in the last four centuries is Nephilis, an Alpha Vampire who eluded Vampire hunters for well over 300 years.
Nephilis was born in present-day Germany in 1688 and grew up in a world of privilege as Wolrad, Count of Ottweiler. At 6'6" tall, he was a commanding presence and a noted patron of the arts. He also was a notorious womanizer whose exploits earned him the ire of many a cuckolded husband. Fortunately for him, he was an outstanding swordsman and never lost a duel. Wolrad's libidinous pursuits finally landed him in real trouble in 1715, when he was turned by a Vampiric prostitute.
The former Wolrad embraced the life of a Vampire and changed his name to Nephilis, a nod to the race of beasts in the Bible known as the Nephilim. As was customary among Vampires at the time, Nephilis "hid in plain sight." He moved easily through the upper crust of society and eventually married a Hapsburg princess named Elzbieta. He turned her on their wedding night and they lived together for more than 150 years.
Despite Nephilis' stature in society, his activities inevitably drew unwelcome attention and he had to move his base frequently; he lived, for a time, in Amsterdam, London and Madrid. Nephilis' life in Europe came to an end when the King of Spain put a bounty on his head. He made his way to America in the hold of a clipper ship and resumed his pattern of finding wealthy patrons to harbor him until the scrutiny of law enforcement forced him to move on. In the 20th century, he increasingly associated himself with bars, speakeasies and nightclubs, where his nocturnal lifestyle wouldn't stand out and where he could easily lure fresh blood. Since he had always been astute at moving around his vast fortune to avoid seizure, he never had trouble buying property or bribing the right people.
Nephilis saw himself as the Vampire Messiah that Quadilla had written of in the Middle Ages. He spoke 12 languages fluently, was a virtuoso on the piano and was able to attract followers and benefactors with his easy charm. Like a Vampiric Forrest Gump, he was allegedly present at many historical events, including the sacking of the Bastille in Paris (1789), the first performance of Beethoven's Ninth Symphony in Vienna (1824), and the San Francisco earthquake and fire of 1906.
Law enforcement hounded Nephilis relentlessly through the 1950s and 1960s. Their closest call came almost by accident in 1971, when a team of FBI agents stumbled upon his base during a rescue operation at a New York City nightclub. However, Nephilis killed an agent and escaped by leaping atop a moving subway train. After he fled, agents were shocked to discover a labyrinthine complex under the nightclub, including a chapel decorated with human skulls, a pit for live captives and a laboratory where the legendary Vampire appeared to be trying to develop a daywalking serum. Since then, there have been no sightings of him.